In bioprocess development for the production of pharmaceuticals, proteins, or nutritional additives, scale-down models are used to save time and costs when testing for suitable cell lines, media ...

image: Researchers from the University of Tsukuba have found that flame-sterilizing shake-flasks, to avoid introducing microbial contaminants, considerably increases the carbon dioxide concentration ...

While industrial bioprocesses have been operated in fed-batch mode for a long time, the screening of high-producer cell lines and a lot of other development work is still performed in batch mode for a ...