Astrocytes reveal fragile X pathway tied to seizures and synapse problems

Fragile X syndrome (FXS) is an inherited genetic developmental condition that strongly impacts brain development. Despite the syndrome stemming from an altered genetic code for the single protein ...

Spinogenix Announces CLARITY: a Phase 2b/3 trial of SPG601 for the Treatment of Fragile X Syndrome

Spinogenix, Inc., a clinical-stage biopharmaceutical company pioneering first-in-class therapeutics designed to restore synapses to improve the lives of patients, is initiating CLARITY, a Phase 2b/3 ...
Yahoo

Fragile X syndrome often results from improperly processed genetic material – correctly cutting RNA offers a potential treatment

Add Yahoo as a preferred source to see more of our stories on Google. For many people with fragile X, the mutated gene that causes symptoms is active rather than silenced. Thom Leach/Science Photo ...

Spinogenix’s Fragile X Syndrome drug shows normalisation of brain function

Spinogenix’s Fragile X Syndrome (FXS) drug is the first to show rescued well-established resting EEG abnormalities, ...
Business Wire

Zatolmilast, an Investigational Treatment for Fragile X Syndrome, Receives Rare Pediatric Disease Designation from the U.S. FDA

OSAKA, Japan--(BUSINESS WIRE)--Shionogi & Co., Ltd. (Head Office: Osaka, Japan; Chief Executive Officer: Isao Teshirogi, Ph.D.; hereafter "Shionogi") announced the U ...
Mirage News

Astrocytes' Role in Fragile X Syndrome Unveiled

Fragile X syndrome (FXS) is an inherited genetic developmental condition that strongly impacts brain development. Despite ...
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Fragile X Syndrome: Symptoms, Diagnosis, Treatments and Complications

Fragile X Syndrome: Symptoms, Diagnosis, Treatments and Complications: By Shreoshree Chakrabarty Fragile X Syndrome (FXS), also known as FX syndrome or fragile syndrome, is the most common inherited ...
Healio

FDA grants orphan designation to Fragile X syndrome therapeutic

Please provide your email address to receive an email when new articles are posted on . The FDA has granted orphan drug designation to a small molecule therapeutic for individuals with Fragile X ...
News Medical

Fragile X syndrome may be unfolding in brain cells even before birth

Fragile X syndrome, the most common form of inherited intellectual disability, may be unfolding in brain cells even before birth, despite typically going undiagnosed until age 3 or later. A new study ...
pharmaphorum

Neuroplasticity modulators as innovative potential disease-modifying treatments for Fragile X Syndrome and other CNS disorders

In September last year, we reported Servier had advanced its emerging neurology pipeline into the clinical trials stage by ...
Science Daily

Antisense therapy restores fragile X protein production in human cells

An antisense therapy restores production of the protein FMRP in cell samples taken from patients with fragile X syndrome. This breakthrough was possible because of the novel findings, also presented ...
news.ucsc

Study implicates glial cells in fragile X syndrome

Research on fragile X syndrome, the most common inherited cause of mental retardation, has focused mostly on how the genetic defect alters the functioning of neurons in the brain. A new study focusing ...