Nerve cells in the brain demand an enormous amount of energy to survive and maintain their connections for communicating with other nerve cells. In Alzheimer's disease, the ability to make energy is ...

The brain runs on energy. Every thought, memory, or emotion sparks countless signals between nerve cells. That communication demands a steady, powerful fuel supply. Without it, the system breaks down.

The Role of Succinate and the Krebs Cycle One key discovery was a bottleneck in the Krebs cycle, specifically in the production of succinate, a molecule crucial for generating ATP—the primary energy ...

Alzheimer's nerve cells manifest a decrease in the connections between nerve cells, called synapses, shown here within the blue circles. Half the synapse is marked with a red fluorescent stain and the ...

If you took biochemistry classes, chances are good you remember memorizing the Krebs cycle, a well-known metabolic pathway in which sugars are converted through a series of steps to generate ATP, a ...

A stressful year leads to anxiety. Lasting isolation gives way to depression. An old trauma nags until it becomes paralyzing.

The ER is the protein synthesis and processing center of a cell. There are two types of ER in a cell: rough ER and smooth ER. The rough ER membrane is studded with ribosomes, which are molecular ...