At the AAIC conference held 27 July to 1 August in Philadelphia, microglial epigenetics stood in the limelight. Microglia are infamous for their dynamic and varied responses to different threats they ...

Scientists discovered that lowering a specific molecule helps microglia switch into a protective state that quiets brain inflammation in Alzheimer’s. A small group of these cells seems to have an ...

Alzheimer's disease (AD) is a highly debilitating neurodegenerative disease characterized by the progressive loss of memory and decline of mental functions. Earlier research has uncovered some of the ...

(Left) Correction of pathogenic Csf1r mutation by Mr BMT effectively rescues pathological changes in the brain, motor impairment and cognitive decline in ALSP mice. (Right) tBMT-mediated microglia ...

It’s hard to overstate how crucial microglia are to brain health. These humble immune cells quietly patrol the central nervous system, clearing debris, pruning synapses, and maintaining myelin. But ...

A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer's disease and other neurological disorders, according to scientists. By engineering human ...

Microglial cells are the maintenance workers of the central nervous system (CNS), protecting against pathogens and pruning damaged neurons to help the brain maintain homeostasis. Considered immune ...

Immune cells in the blood may be intimately involved with Alzheimer’s pathogenesis in the brain. At least, according to their chromatin. A study published January 31 in Neuron reported that in people ...