Chronic stress and social isolation are frequently cited as precursors to physical illness, yet the biological machinery ...

Scientists are no longer just cataloging the damage that comes with age, they are starting to rewire the machinery inside ...

Eustachian tube dysfunction often determines whether a routine ear infection clears quickly or develops into a persistent ...

Jeffrey Rathmell, PhD, left, and Darren Heintzman have defined the molecular events of the T cell response to fever temperatures. Fever temperatures rev up immune cell metabolism, proliferation and ...

Normal metabolic activity produces reactive oxygen species (ROS) that, if not eliminated, can damage cellular components. As a result, ROS from overactive mitochondria are frequently cited as a source ...

Mitochondrial defects are associated with the development of diseases such as type 2 diabetes (T2D). Studies in mice and in human tissues, by researchers at the University of Michigan, have now found ...

Multiple sclerosis (MS) affects an estimated 2.3 million people worldwide. Approximately 80% of people with MS have inflammation in the cerebellum, the part of the brain that helps control movement ...

The mitochondrial protein COX7RP may increase healthspan in mice, a new study reports.

Researchers outline why organs from older donors are often discarded and identify the biological and immunological pathways ...

Mayo Clinic researchers have uncovered how aging "zombie cells" trigger harmful inflammation that accelerates a severe and ...