A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. This discovery ...
Despite the significance of immune checkpoint inhibitors (ICIs) in solid tumor treatment, identifying ICI-sensitive populations remains a challenge. Mutations in DNA damage response (DDR) pathway ...
DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among ...
BOSTON--(BUSINESS WIRE)--Genialis, the RNA biomarker company, today announced an extension of its collaboration with Debiopharm, a Swiss-based global biopharmaceutical company, to develop a predictive ...
Cells are not immortal, and that is a good thing. After a certain number of divisions, many human cells stop multiplying for ...
When cell division (mitosis) takes too long, it can be a sign that something is wrong with the cells, for example, DNA damage ...
EPFL scientists have identified a molecular pathway that protects cells from lipid oxidation and ferroptosis, a regulated ...
Validation of a 15-Gene Prognostic Signature in Metastatic Clear Cell Renal Cell Carcinoma Despite the significance of immune checkpoint inhibitors (ICIs) in solid tumor treatment, identifying ...