Myotonic dystrophy type 1 (DM1) is the most common form of adult-onset muscular dystrophy, affecting about 1 in 8,000 people.

Numerous motor and structural proteins compose a highly ordered structure known as the sarcomere, the basic unit of muscle contraction in heart and skeletal muscles. Sarcomeric myosin heavy chain ...

A new swtudy sheds light onto the causes and potential solutions to the GI problems associated with myotonic dystrophy type 1 (DM1), the most common form of adult-onset muscular dystrophy, affecting ...

About EDG-5506 EDG-5506 is an orally administered small molecule designed to prevent muscle damage induced by mechanical stress in dystrophinopathies including DMD and BMD. EDG-5506 presents a novel ...

Skeletal muscle is a dynamic and highly adaptable tissue responsible for voluntary movement, posture and metabolic regulation. Its unique architecture, involving myofibres, satellite cells and a ...

Researchers describe a new mechanism for muscle repair after physiological damage relying on the rearrangement of muscle fibre nuclei, and independently of muscle stem cells. Muscle is known to ...

SINCE Lundsgaard showed that the contractile mechanism can work without production of lactic acid and that this acid, when formed, appears mainly, perhaps entirely, after contraction is over, the one ...

A new study by researchers at Yale and Johns Hopkins University has discovered how asthmatic bronchial spasms — muscle contractions in the airway that cause difficulty breathing in asthma patients— ...

MHH scientist investigates how pro-inflammatory cytokines interfere with muscle metabolism and actively transform muscles.

Researchers have just made the unexpected discovery of a novel organization of muscle fibers in Parophidion vassali, a fish that lives in the Mediterranean Sea and, like many fish, uses specialized ...