A recent study, undertaken by researchers at the Tokyo Metropolitan University and the Tokyo Metropolitan Institute of Medical Science (both Japan), unravels key steps in the process of homologous ...
Researchers have revealed the structural mechanisms of a major DNA repair pathway in human cells. The research, published today as a Reviewed Preprint in eLife, is described by the editors as a ...
The above representative microscope images showcase ultra-fine bridges, a kind of abnormal link between chromosomes that causes catastrophic genetic instability. These bridges, composed of entangled ...
Impact of Genomic Alterations on Efficacy of Trastuzumab Deruxtecan Against Human Epidermal Growth Factor Receptor-2–Positive Advanced Gastric Cancer This was a prospective, cross-sectional, ...
The ability of the Geneva homologous recombination deficiency (HRD) test to predict progression-free survival (PFS) in patients with high-grade ovarian cancer treated with poly (ADP-ribose) polymerase ...
One of the biggest challenges in cancer treatment is chemoresistance: Tumors that initially respond well to chemotherapy become resistant over time. When that happens, treatment options are often ...
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