pharmaphorum

Humanized FcRn Mice: promising tools for evaluating the pharmacokinetics of monoclonal antibodies

Ray Lambert looks at the potential of humanized FcRn mice for evaluating the pharmacokinetics of mAbs. Due to their extraordinary specificity and pharmacokinetic (PK) behavior, human immunoglobulin ...
EurekAlert!

Reduced human-body advantage in mental rotation among patients with knee osteoarthritis

Patients with knee osteoarthritis and a healthy control group participated in mental rotation tests to assess human-body advantage using stimuli. Mental rotation can be performed more efficiently for ...
Nature

A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor

Figure 1: The TCR is specific for the HLA-DR2:MBP peptide complex. An Il-2 ELISPOT assay showed that approximately 0.5% of CD4-positive T cells in DR2/TCR double-transgenic mice and DR2/TCR/CD4 triple ...
IEEE

CenterNet++ for Object Detection

Abstract: There are two mainstream approaches for object detection: top-down and bottom-up. The state-of-the-art approaches are mainly top-down methods. In this paper, we demonstrate that bottom-up ...
Beebom

I Tried 40+ Tools and Only These 7 Best AI Humanizers Pass Detection

I don’t advocate using AI to write content, but sometimes it can help you articulate your point better. However, spotting AI-written content is extremely easy, since it uses nuanced words, em dashes, ...
IEEE

YOLOv7: Trainable Bag-of-Freebies Sets New State-of-the-Art for Real-Time Object Detectors

Abstract: Real-time object detection is one of the most important research topics in computer vision. As new approaches regarding architecture optimization and training optimization are continually ...